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背景：到目前为止,还没有一种十分有效的方法治疗关节软骨缺损。许多治疗方法都只能缓解临床症状,而不能有效促进软骨的再生,也不能恢复软骨表面的承重功能。目的：观察脱钙骨基质复合骨髓间充质干细胞修复兔膝关节全层软骨缺损的疗效。设计、时间及地点：随机对照动物实验,分别于2005—01／03在兰州大学第二医院骨科研究所和2008-05／08在桂林医学院中心实验室完成。材料：取

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