2011英国高血压指南(3)

来源：网络收集时间：2026-06-29

导读： Evidencestatementsinthissummaryrelatetotheguidelineupdate.QualityratingswerebasedonGRADEmethodology().Theserelatetothequalityoftheavailableevidenceforassessedoutcomesratherthanthequalityoftheclinical

Evidencestatementsinthissummaryrelatetotheguidelineupdate.QualityratingswerebasedonGRADEmethodology().Theserelatetothequalityoftheavailableevidenceforassessedoutcomesratherthanthequalityoftheclinicalstudy.Outcomesassessedincludedmortality,heartfailure,newonsetdiabetesmellitus,vascularprocedures,angina,healthrelatedqualityoflife,andbloodpressureresponsetotreatment.Costeffectivenessanalysisformethodofdiagnosis

Aneconomicmodelwasdevelopedtocomparethecosteffectivenessofthreedifferentoptionsforbloodpressuremeasurementfordiagnosinghypertension:clinic,home,andambulatorybloodpressuremonitoring.Ambulatorybloodpressuremonitoringwasthemostcosteffectivestrategyformenandwomenofallages.Itwascostsavingforallagesconsideredforbothmenandwomenandresultedinmorequalityadjustedlifeyears(QALYs)formaleandfemaleagegroupsover50.Thisresultwasrobusttoawiderangeofsensitivityanalysesaroundthebasecasebutwassensitiveifhomemonitoringwasconsideredtohaveequaltestperformancetoambulatorymonitoringoriftreatmentwasconsideredeffectiveinindividualswhowerenothypertensive.Costeffectivenessanalysisforfirstlinedrugtreatment

Theeconomicmodelassessingfirstlinedrugtreatmentdevelopedaspartoftheclinicalguideline344wasupdated.Thiscomparednointervention,ACEinhibitororARB,βblockers,calciumchannelblockers,andthiazide-typediureticsintermsoflifetimecostsandqualityadjustedlifeyears(QALYs)fromaUKhealthserviceperspective.DrugcostswerebasedongenericUKlistprices.Treatinghypertensionwashighlycosteffective,resultinginimprovedhealthoutcomes(moreQALYs)andcostsavingswithalldrugclassescomparedwithnotreatment.Calciumchannelblockerswereshowntobethemostcosteffectiveintervention,withanincrementalcosteffectivenessratioofunder£2000(

2011英国高血压指南(3).doc 将本文的Word文档下载到电脑，方便复制、编辑、收藏和打印

下载这篇word文档

本文链接：https://www.jiaowen.net/wenku/115002.html（转载请注明文章来源）

上一篇：2012年富民幼儿园安全工作计划
下一篇：中国无缝钢管市场深度分析与发展趋势前瞻报告(2014-2019)